Претрага
797 items
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Timok Scientific Tornado- TNT - a model for science popularization and the development of competencies through cooperation with the stakeholders
Ranđelović Dragan, Randjelović Nataša, Ranđelović Dragana. "Timok Scientific Tornado- TNT - a model for science popularization and the development of competencies through cooperation with the stakeholders" in Proceedings of XXV International Conference on Ecological Truth, :Univerzitet u Beogradu, Tehnički fakultet u Boru Univerzitet u Beogradu, Tehnički fakultet u Boru (2017): 478-484
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Overcoming the Low Oral Bioavailability of Deuterated Pyrazoloquinolinone Ligand DK-I-60-3 by Nanonization: A Knowledge-Based Approach
Jelena R. Mitrović , Branka Divović-Matović, Daniel E. Knutson, Jelena B. Ðoković, Aleksandar Kremenović, Vladimir D. Dobričić, Danijela V. Randjelović, Ivana Pantelić, James M. Cook, Miroslav M. Savić, Snežana D. Savić (2021)Poor water solubility of new chemical entities is considered as one of the main obstacles in drug development, as it usually leads to low bioavailability after administration. To overcome these problems, the selection of the appropriate formulation technology needs to be based on the physicochemical properties of the drug and introduced in the early stages of drug research. One example of the new potential drug substance with poor solubility is DK-I-60-3, deuterated pyrazoloquinolinone, designed for the treatment of various neuropsychiatric ...... Approach Jelena R. Mitrović , Branka Divović-Matović, Daniel E. Knutson, Jelena B. Ðoković, Aleksandar Kremenović, Vladimir D. Dobričić, Danijela V. Randjelović, Ivana Pantelić, James M. Cook, Miroslav M. Savić, Snežana D. Savić Дигитални репозиторијум Рударско-геолошког факултета Универзитета у ...
... Approach | Jelena R. Mitrović , Branka Divović-Matović, Daniel E. Knutson, Jelena B. Ðoković, Aleksandar Kremenović, Vladimir D. Dobričić, Danijela V. Randjelović, Ivana Pantelić, James M. Cook, Miroslav M. Savić, Snežana D. Savić | Pharmaceutics | 2021 | | 10.3390/pharmaceutics13081188 http://dr.rgf ...
... Jelena R. Mitrović 1, Branka Divović-Matović 2, Daniel E. Knutson 3 , Jelena B. Ðoković 1, Aleksandar Kremenović 4 , Vladimir D. Dobričić 5, Danijela V. Randjelović 6, Ivana Pantelić 1 , James M. Cook 3 , Miroslav M. Savić 2 and Snežana D. Savić 1,* ���������� ������� Citation: Mitrović, ...Jelena R. Mitrović , Branka Divović-Matović, Daniel E. Knutson, Jelena B. Ðoković, Aleksandar Kremenović, Vladimir D. Dobričić, Danijela V. Randjelović, Ivana Pantelić, James M. Cook, Miroslav M. Savić, Snežana D. Savić. "Overcoming the Low Oral Bioavailability of Deuterated Pyrazoloquinolinone Ligand DK-I-60-3 by Nanonization: A Knowledge-Based Approach" in Pharmaceutics, MDPI, Basel, Switzerland (2021). https://doi.org/10.3390/pharmaceutics13081188
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Curcumin nanonization using an alternative small-scale production unit: selection of proper stabilizer applying basic physicochemical consideration and biological activity assessment of nanocrystals
Ines Nikolić, Jelena Antić-Stanković, Dragana Božić, Danijela Ranđelović, Bojan Marković, Dominique Jasmin Lunter, Aleksandar Kremenović, Miroslav Savić, Snežana Savić (2020)As the number of poorly soluble drugs is increasing, nanocrystals have become very interesting due to wide range of application possibilities. Curcumin was used as a model active ingredient in this work. Even though it has many proven positive effects, due to its physicochemical issues, its possibilities have not been fully exploited. The goal of this work was to select optimal conditions for a top-down method for curcumin nanosuspension production, and to perform their comprehensive characterization applying complementary methodologies: ...Ines Nikolić, Jelena Antić-Stanković, Dragana Božić, Danijela Ranđelović, Bojan Marković, Dominique Jasmin Lunter, Aleksandar Kremenović, Miroslav Savić, Snežana Savić. "Curcumin nanonization using an alternative small-scale production unit: selection of proper stabilizer applying basic physicochemical consideration and biological activity assessment of nanocrystals" in Review on advanced materials science, Walter de Gruyter GmbH (2020). https://doi.org/10.1515/rams-2020-0043
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Geotehnička istraživanja terena za potrebe izgradnje mosta preko Aleksandrovačkog potoka na autoputu E-80, deonica Niš-Merošina
Danijela Sušić (2023)Geotehnička istraživanja terena, odnosno određene lokacije, izvode se za potrebe projektovanja, odnosno definisanja uslova izgradnje objekata. Njihova osnovna namjena jeste upoznavanje i prikupljanje informacija o sastavu i svojstvima geološke sredine koje bi mogle da nam omoguće planiranje, projektovanje, izgradnju, kao i racionalno korišćenje samog objekta. U ovom radu, detaljno je prikazan način svih izvršenih istraživanja, za potrebe izgradnje mosta na osnovu kojih je urađen grafički dio, proračun nosivosti plitko fundiranog mosta i proračun analize slijeganja terena. Za proračun dozvoljenog opterećenja ...geotehnička istraživanja, terenska istraživanja, laboratorijska ispitivanja, geotehnički model terena, plitki temeljiDanijela Sušić. Geotehnička istraživanja terena za potrebe izgradnje mosta preko Aleksandrovačkog potoka na autoputu E-80, deonica Niš-Merošina, 2023
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Improvement of education through the cooperation between CEEPUS EURO Geo-Sci network and scientific projects: examples from UB-FMG
Kristina Šarić, Dejan Prelević, Miloš Marjanović, Uroš Stojadinović, Vladimir Simić . "Improvement of education through the cooperation between CEEPUS EURO Geo-Sci network and scientific projects: examples from UB-FMG" in V Congress of Geologists of Republic of Macedonia ": “Geology in a changing world”, Makedonsko geološko društvo (2024)
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The influence of Al<sup>3+</sup>ion on porcine pepsin activity<i>in vitro</i>
The in vitro effect of Al3þ ions in the concentration range 1.7·1026M–8.7·1023M on pepsin activity at pH 2, via kinetic parameters and its electrophoretic mobility was evaluated. Kinetic study demonstrated the existence of an activation effect of Al3þ at pH 2 on pepsin molecule. Kinetic analysis with respect to concentrations of haemoglobin showed that Al3þ ions increase the maximal velocity (Vmax) and kcat values rather than apparent affinity for substrate (KS) implying the non-competitive nature of activation which indicated ...... Pavelkić, Kristina R. Gopcević, Danijela Z. Krstić, Marija A. Ilić Дигитални репозиторијум Рударско-геолошког факултета Универзитета у Београду [ДР РГФ] The influence of Al3+ion on porcine pepsin activityin vitro | Vesna M. Pavelkić, Kristina R. Gopcević, Danijela Z. Krstić, Marija A. Ilić | Journal ...
... informa healthcare • 3+ • • • •. B •. The influence of A' ion on porcine pepsin activity 2? TfO VESNA M. PAVELKIC!, KRISTINA R. GOPCEVIC?, DANIJELA Z. KRSTIC?, & MARIJA A. ILIC? lDepartmem of Physical Chemistry, Vinca-pInstitute of Nuclear Science, POB 522, 11001 Belgrade, Serbia, ŽSchool of ...
... addition of different concentrations of AP? ion (1, 5 and 10mM). "The samples of pepsin and haemoglobin were diluted with sample buffer in ratio 1:1 (v/v) and applied on gel in volume of 20 uL. Visualization was performed with Commassie Brilliant Blue G-250 dye. The gels scanned and processed using ...Vesna M. Pavelkić, Kristina R. Gopcević, Danijela Z. Krstić, Marija A. Ilić. "The influence of Al3+ion on porcine pepsin activityin vitro" in Journal of Enzyme Inhibition and Medicinal Chemistry, Informa UK Limited (2008). https://doi.org/10.1080/14756360701841095
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Open Educational Resources in Serbia
... Obradović, Ranka Stanković, Marija Blagojević, Danijela Milošević Дигитални репозиторијум Рударско-геолошког факултета Универзитета у Београду [ДР РГФ] Open Educational Resources in Serbia | Ivan Obradović, Ranka Stanković, Marija Blagojević, Danijela Milošević | Current State of Open Educational ...
... international project and project coordinator for one project. Danijela Milošević University of Kragujevac, Faculty of Technical Sciences Čačak Svetog Save 65, 32 000 Čačak danijela.milosevic@ftn.kg.ac.rs +38130302757 Danijela Milošević is full professor and dean at the Faculty of Technical ...
... Chapter # - will be assigend by editors OPEN EDUCATIONAL RESOURCES IN SERBIA AUTHOR(s) - Ivan Obradović, Ranka Stanković, Marija Blagojević, Danijela Milošević Abstract: This chapter provides a review of open educational resources in Serbia. It covers different aspects of open educational ...Ivan Obradović, Ranka Stanković, Marija Blagojević, Danijela Milošević. "Open Educational Resources in Serbia" in Current State of Open Educational Resources in the “Belt and Road” Countries, Springer Singapore (2020). https://doi.org/10.1007/978-981-15-3040-1_10
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Geodynamics of basins above subducted slabs: An integrated modelling study of tectonics, sedimentation, and magmatism in the Timok Magmatic Complex
Uros Stojadinovic, Marinko Toljic, Branislav Trivic, Radoje Pantovic, Danica Sreckovic-Batocanin, Nemanja Krstekanic, Bojan Kostic, Milos Velojic, Jelena Stefanovic, Nikola Randjelovic, Maja Males (2024)Uros Stojadinovic, Marinko Toljic, Branislav Trivic, Radoje Pantovic, Danica Sreckovic-Batocanin, Nemanja Krstekanic, Bojan Kostic, Milos Velojic, Jelena Stefanovic, Nikola Randjelovic, Maja Males. "Geodynamics of basins above subducted slabs: An integrated modelling study of tectonics, sedimentation, and magmatism in the Timok Magmatic Complex" in Annales geologiques de la Peninsule balkanique, National Library of Serbia (2024). https://doi.org/10.2298/GABP240116003S
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Exhumation history of the Juhor Mts. in central Serbia, the Northern Serbo–Macedonian Subunit
Uros Stojadinovic, Hannah Pomella, Nemanja Krstekanić, Bojan Kostić, Maja Maleš, Nikola Randjelovic, Miloš Radonjić (2024)Northern Serbo–Macedonian Subunit, low-t thermochronology, kinematic analyses, extensional deformationsUros Stojadinovic, Hannah Pomella, Nemanja Krstekanić, Bojan Kostić, Maja Maleš, Nikola Randjelovic, Miloš Radonjić. "Exhumation history of the Juhor Mts. in central Serbia, the Northern Serbo–Macedonian Subunit" in Geologica Carpathica, Jun 2024, Central Library of the Slovak Academy of Sciences (2024). https://doi.org/10.31577/GeolCarp.2024.12
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Natural values of tourism development on the Shara-mountain
Vukoičić Danijela, Srećković Batoćanin Danica, Kićović Dragomir. "Natural values of tourism development on the Shara-mountain" in 2nd Serbian Geographers Congress Towards Europe = 2. kongres geografa Srbije Na putu ka Evropi, 10th and 11th December, 2010 : Abstract book, Novi Sad:Univerzitet u Novom Sadu, Geografski fakultet (2010): 124-124
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Prirodne vrednosti za razvoj turizma na Šar-planini (Natural values for tourism development on the Šar-mountains)
Vukoičić Danijela, Kićović Dragomir, Srećković Batoćanin Danica. "Prirodne vrednosti za razvoj turizma na Šar-planini (Natural values for tourism development on the Šar-mountains)" in Туристично пословање = Tourism business no. 7, Београд:Висока туристичка школа струковних студија (2011): 67-79
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Freeze-dried nanocrystal dispersion of novel deuterated pyrazoloquinolinone ligand (DK-I-56-1): Process parameters and lyoprotectant selection through the stability study
Jelena R. Mitrović, Maja Bjelošević Žiberna, Aleksandar Vukadinović, Daniel E. Knutson, Dishary Sharmin, Aleksandar Kremenović, Pegi Ahlin Grabnar, Odon Planinšek, Dominique Lunter, James M. Cook, Miroslav M. Savić, Snežana D. Savić (2023)Recently, nanocrystal dispersions have been considered as a promising formulation strategy to improve the bioavailability of the deuterated pyrazoloquinolinone ligand DK-I-56-1 (7‑methoxy-2-(4‑methoxy-d3-phenyl)-2,5-dihydro-3H-pyrazolo[4,3-c]quinolin-3-one). In the current study, the freeze-drying process (formulation and process parameters) was investigated to improve the storage stability of the previously developed formulation. Different combinations of lyoprotectant (sucrose or trehalose) and bulking agent (mannitol) were varied while formulations were freeze-dried under two conditions (primary drying at -10 or -45 °C). The obtained lyophilizates were characterized in terms ...... Pharm. 566, 254–263. https://doi.org/10.1016//j.ijpharm.2019.05.065. Mitrović, J.R., Divović, B., Knutson, D.E., Đoković, J.B., Vulić, P.J., Randjelović, D.V., Dobričić, V.D., Čalija, B.R., Cook, J.M., Savić, M.M., Savić, S.D., 2020. Nanocrystal dispersion of DK-I-56-1, a poorly soluble pyrazol ...
... ultrapure water (1:100, v/v). Reconstitution and particle size mea- surement were performed right after freeze-drying, and one and three months after freeze-drying. The redispersibility index (RDI) was calcu- lated using the following equation: dVebefore byo + _O be v 100 Z — aVčafterlyo RDI(%) ...
... T25 digital (IKAR-Werke GmbH & Company KG) at 10 000 rpm for 5 min. The obtained dispersion was transferred to 2 ml Eppendorf tubes containing 60% v/v 0.1-0.2 mm yttrium-stabilized zirconium beads (SiLibeads8 type ZY-S, Sigmund Lindner, Germany). To reduce the particle size, the tubes were shaken ...Jelena R. Mitrović, Maja Bjelošević Žiberna, Aleksandar Vukadinović, Daniel E. Knutson, Dishary Sharmin, Aleksandar Kremenović, Pegi Ahlin Grabnar, Odon Planinšek, Dominique Lunter, James M. Cook, Miroslav M. Savić, Snežana D. Savić. "Freeze-dried nanocrystal dispersion of novel deuterated pyrazoloquinolinone ligand (DK-I-56-1): Process parameters and lyoprotectant selection through the stability study" in European Journal of Pharmaceutical Sciences, Elsevier BV (2023). https://doi.org/10.1016/j.ejps.2023.106557
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The evaluation of geosites in the territory of National Park „Kopaonik“(Serbia)
Vukoičić Danijela, Milosavljević Saša, Valjarević Aleksandar, Nikolić Milena, Srećković-Batoćanin Danica (2018)Vukoičić Danijela, Milosavljević Saša, Valjarević Aleksandar, Nikolić Milena, Srećković-Batoćanin Danica. "The evaluation of geosites in the territory of National Park „Kopaonik“(Serbia)" in Open Geosciences 10 no. 1, Krakow, Poland:DE GRUYTER Poland (2018): 618-633. https://doi.org/10.1515/geo-2018-0049
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Đavolja varoš-istorija stvaranja i potencijali
Srećković Batoćanin Danica, Vukoičić Danijela, Papović Olivera, Milovanović Dragan, Kićović Dragomir, Đekić Tatjana (2010)Srećković Batoćanin Danica, Vukoičić Danijela, Papović Olivera, Milovanović Dragan, Kićović Dragomir, Đekić Tatjana. "Đavolja varoš-istorija stvaranja i potencijali" in Geoekologija XXI vijeka : teorijski i aplikativni zadaci : zbornik referata : radovi su objavljeni u obliku dobijeno od autora, Nikšić:Filozofski fakultet (2010): 257-268
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Assessment of the Geotouristic Values of Devil’s Town, Serbia
Danijela Vukoičić, Danica Srećković-Batoćanin, Aleksandar Valjarević, Dušan Ristić, Milena Nikolić, Dragana Valjarević (2021)Geotouriyam, Geonasledje, M-GAM, Komparativna analiya, Đavolja Varoš, Peščane piramide, Stob Piramide, Melnik piramide, SrbijaDanijela Vukoičić, Danica Srećković-Batoćanin, Aleksandar Valjarević, Dušan Ristić, Milena Nikolić, Dragana Valjarević. "Assessment of the Geotouristic Values of Devil’s Town, Serbia" in Geologia Croatica, Croatian Geological Survey (2021). https://doi.org/10.4154/gc.2021.11
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Analysis of a simplified model for determining rock mass oscillation velocity at the Kovilovača open pit
... registered rock mass oscillation velocities v, is given, as well as calculated rock mass oscillation velocities from v,, to v,s , for models 1 — 5. Table 3. Review of registered and calculated rock mass oscillation velocities for models 1-5 V, [cm/s| a [cm/s V;s [cm/s] 21.8117 55.3430 55.9536 ...
... component, • V, — rock mass oscillation velocity vertical component, • Y, — rock mass oscillation velocity horizontal longitudinal component. Based on that, maximum, i.e., resulting rock mass oscillation velocity V, can be determined using following equation: 2 2 2 V,OS NM +V TV 3 Q) 3. ROCK ...
... explosive Q , calculated values of reduced distances R., registered values of rock mass oscillation velocities per components V,, V,, V, and resulted rock mass oscillation velocities v, for blasting I — I, at the total of ten measured points MP, are presented in Table 2. 200 Table 2. Review of blasting ...Suzana Lutovac, Miloš Gligorić, Jelena Majstorović, Luka Crnogorac. "Analysis of a simplified model for determining rock mass oscillation velocity at the Kovilovača open pit" in 9th International Conference Mining and Environmental protection MEP, 24 – 27 May 2023, Sokobanja, Serbia, Belgrade : University of Belgrade-Faculty of mining and geology (2023)
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Threshold-induced correlations in the Random Field Ising Model
... ˆT i b V T i V b S i b V b S i V(S ; ) ( ; )/ , (S ; ) ( ; ), (4)b x b x x th th th 1 th hold for the duration T(i; Vth) and size ∫= ′ ′ −S i V f t dt V T i V( ; ) ( ) ( ; ) t t ith th th s e , and also for the following types of waiting times: = = = ˆ ˆ ˆ T i b V T i V b T i b V T i V ...
... =ζ ζ+ − + −D T b b V b b D T V D b S b V b b D S V( / ; , ) ( ; , ), ( ; , ) ( ; , ), (13)T x w T S x x w x Sth 1 th 1 th 1 th λ λ=ζ +D T b b V b b D T V( / ; , ) ( ; , ), (14)T x w Tint th 1 int thint int λ λ λ λ = = . ζ ζ + + D T b b V b b D T V D T b b V b b D T V ( / ; , ) ( ; , ...
... )i T( ) int th int , n T V( ; )i T( ) end th end , and n T V( ; )i T( ) ini th ini corresponding to internal waiting time Tint, and contributions Tend and Tini to the external waiting time, respectively. �ese numbers obey: = =− ˆ ˆn T b b V n T V n b S b V n S V( / ; ) ( ; ), ( ; ) ( ; ), (8)i ...Sanja Janićević, Dragutin Jovković, Lasse Laurson, Đorđe Spasojević. "Threshold-induced correlations in the Random Field Ising Model" in Scientific Reports, Springer Science and Business Media LLC (2018). https://doi.org/10.1038/s41598-018-20759-6
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Parameter determination of soil oscillation law using quotient of the relative growth increments of oscillation velocity and reduced distances at “Nepričava“ open pit mine
... operation of relation (10) we obtain: 1 21 1 2 1 ... log log ... N N N N v v vR n R R R v where we find: 1 2 1 1 1 2 ... log log ... N N N N v v v v n R R R R (11) By the replacement ...
... R1, i = 2, 3, ..., N, from the equation (9), we can take that: 1 1 2,3,..., n i i R v v i N R from where the relation is obtained: 1 1 2 1 1 2 ... ... n N N N N R v v v v R R R (10) From the relation (10), we can determine ...
... have approximately the same value (Lutovac, 2010) which will be marked (-n), meaning that: v v n R R (2) Thereby it can be considered that: 0 lim R v v n R R which means that is: 12 ...Suzana Lutovac, Sanja Bajić, Marina Ravilić, Radmila Gaćina. "Parameter determination of soil oscillation law using quotient of the relative growth increments of oscillation velocity and reduced distances at “Nepričava“ open pit mine" in Underground Mining Engineering, Belgrade : University of Belgrade, Faculty of Mining and Geology (2015). https://doi.org/10.5937/podrad1526009L
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Models of Determining the Parameters of Rock Mass Oscillation Equation with Experimental and Mass Blastings
... 1%, the oscillation velocity of the soil v will decrease (increase) by approximately n% [8]. Indeed, for h = ± R 100 = ±1%R, from (12) we obtain: v ( R ± R 100 ) ≈ v(R)∓ n· R 100 · v(R) R , v ( R ± R 100 ) ≈ v(R)∓ n· v(R) 100 , v(R ± 1%R) ≈ v(R)∓ n%·v(R). (14) 3.3. Models to Determine the ...
... applied to the function v(R) from (7), in the final growth increment, we obtain: v(R + h) ≈ v(R) + h·v′(R + θ·h), 0 < θ < 1. (11) For small absolute values h, from (11), we obtain the relation: v(R + h) ≈ v(R) + h·v′(R). (12) Having (10) in mind, relation (12) becomes: v(R + h) ≈ v(R)− n·h·v(R) R . (13) ...
... written in the form: v(R) = K-R™. (7) Then from the Equation (7) for the derivation v’(R), we obtain: o'(R) = —n-K-R-"1, (8) Minerals 2018, 8, 70 5 of 18 which may be written in the form: v′(R) = − n R ·K·R−n. (9) Having in mind Equation (7), from the Equation (9), we obtain: v′(R) = −n·v(R) R ...Suzana Lutovac, Branko Gluščević, Rade Tokalić, Jelena Majstorović, Čedomir Beljić. "Models of Determining the Parameters of Rock Mass Oscillation Equation with Experimental and Mass Blastings" in Minerals, Basel : MDPI AG, Basel, Switzerland (2018). https://doi.org/10.3390/min8020070
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Soil oscillation law parameter determination with the application of Lagrange’s theorem at “Kovilovača“ open pit
... values v(Rs), v(R1), Rs and R1 we take from the table of experimental data, so that we have: c s s Rv v 1 1 R-R v- . (12) In this manner we find a derivative v'(Rc) at point Rc, whereas Rc is given using formula (11). In practice the formula (8) is used so that the values v(Rs) and v(R1) ...
... formuli (8) vrednosti v(Rs), v(R1), Rs i R1 uzimamo iz tabele eksperimentalnih podataka, tako da imamo: c s s Rv v 1 1 R-R v- . (12) Na ovaj način nalazimo izvod v'(Rc) u tački Rc, gde je Rc dato pomoću formule (11). U praksi formulu (8) koristimo tako što vrednosti v(Rs) i v(R1) uzimamo iz ...
... i.e. n RK R n v . (5) Bearing in mind (4), equation (5) is re- duced to: R vn v (6) From (6) the following is found: v R vn (7) If the derivative v' at some point Rc could not be found then from the equation (7), n can be determined. Value of deriva- tive v' can be determined using ...Suzana Lutovac, Nebojša Vidanović, Čedomir Beljić, Zoran Gligorić. "Soil oscillation law parameter determination with the application of Lagrange’s theorem at “Kovilovača“ open pit" in Mining and Metallurgy Engineering Bor, Bor : Mining and Metallurgy Institute Bor (2015). https://doi.org/10.5937/MMEB1503053L