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2351 items
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Overcoming the Low Oral Bioavailability of Deuterated Pyrazoloquinolinone Ligand DK-I-60-3 by Nanonization: A Knowledge-Based Approach
Jelena R. Mitrović , Branka Divović-Matović, Daniel E. Knutson, Jelena B. Ðoković, Aleksandar Kremenović, Vladimir D. Dobričić, Danijela V. Randjelović, Ivana Pantelić, James M. Cook, Miroslav M. Savić, Snežana D. Savić (2021)Poor water solubility of new chemical entities is considered as one of the main obstacles in drug development, as it usually leads to low bioavailability after administration. To overcome these problems, the selection of the appropriate formulation technology needs to be based on the physicochemical properties of the drug and introduced in the early stages of drug research. One example of the new potential drug substance with poor solubility is DK-I-60-3, deuterated pyrazoloquinolinone, designed for the treatment of various neuropsychiatric ...... K., V.D.D., D.V.R., and I.P.; investigation, J.R.M., D.E.K., J.B.Ð., A.K., V.D.D., D.V.R., and I.P.; writing—original draft preparation, J.R.M.; writing—review and editing, A.K., J.M.C., M.M.S., and S.D.S.; funding acquisition, J.M.C., M.M.S., and S.D.S. All authors have read and agreed to the published ...
... of milling solely, one-way ANOVA was conducted and revealed significant influence in formulations F1, F6, and F8, but after performing post hoc tests, the significant difference was noticed only when comparing 20% and 60% bead volumes (F6 and F8) or 20% and 40% (F1). Indeed, when analyzing PDI values, ...
... thermograms of samples S5, F5, F6, and F8 could be associated with residual water and PVP. Pharmaceutics 2021, 13, 1188 12 of 19 Figure 4. DSC thermograms of unprocessed DK-I-60-3, nanocrystal dispersions (F5, F6, and F8), and corresponding suspensions (S5, S6, and S8). To obtain a more detailed insight ...Jelena R. Mitrović , Branka Divović-Matović, Daniel E. Knutson, Jelena B. Ðoković, Aleksandar Kremenović, Vladimir D. Dobričić, Danijela V. Randjelović, Ivana Pantelić, James M. Cook, Miroslav M. Savić, Snežana D. Savić. "Overcoming the Low Oral Bioavailability of Deuterated Pyrazoloquinolinone Ligand DK-I-60-3 by Nanonization: A Knowledge-Based Approach" in Pharmaceutics, MDPI, Basel, Switzerland (2021). https://doi.org/10.3390/pharmaceutics13081188
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Simple 2D gravity–density inversion for the modeling of the basin basement: example from the Banat area, Serbia
We have developed a technique to calculate lateral density distribution of the sedimentary basin basement by combining linear gravity–density inversion and 2D forward modeling. The procedure requires gravity anomaly data, depth-to-basement data and density data for the sediments (density–depth distribution). Gravity efect of density variations in the basement was extracted from the total gravity anomaly by removing the joint efect of the sediments with vertical density variations and homogeneous basement of average density contrast (calculated by 2D modeling). Gravity ...Ivana Vasiljević, Snežana Ignjatović, Dragana Đurić. "Simple 2D gravity–density inversion for the modeling of the basin basement: example from the Banat area, Serbia" in Acta Geophysica, Springer (2019). https://doi.org/10.1007/s11600-019-00328-9
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Development of an integrated model for open-pit-mine discontinuous haulage system optimization
Miodrag Čelebić, Dragoljub Bajić, Sanja Bajić, Mirjana Banković, Duško Torbica, Aleksej Milošević , Dejan Stevanović (2024)Miodrag Čelebić, Dragoljub Bajić, Sanja Bajić, Mirjana Banković, Duško Torbica, Aleksej Milošević , Dejan Stevanović . "Development of an integrated model for open-pit-mine discontinuous haulage system optimization" in Sustainability, MDPI (2024). https://doi.org/10.3390/su16083156
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Numerical Models of Debris Flows with Entrainment Analysis-Case Studies from the Republic of Serbia
The results of material entrainment analysis in RAMMS debris flow software, as well as numerical models of final flow heights for two case studies from the Republic of Serbia are presented. Both of debris flow cases started with initial sliding of huge volume block, prolonging to behave as flowing process. Results of the analysis showed that entrainment material affects final results of transportation model, runout distance, deposition area and volume of debris flow. In both cases entrainment volume is very ...Jelka Krušić , Biljana Abolmasov, Miloš Marjanović. "Numerical Models of Debris Flows with Entrainment Analysis-Case Studies from the Republic of Serbia" in Understanding and Reducing Landslide Disaster Risk. WLF 2020. ICL Contribution to Landslide Disaster Risk Reduction, Springer, Cham (2021). https://doi.org/10.1007/978-3-030-60706-7_25
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Multi-word Expressions for Abusive Speech Detection in Serbian
Ovaj rad predstavlja istraživanja na usavršavanju i unapređenju srpske verzije rečnika Hurtlex, višejezičnog leksikona uvredljivih reči. Posebnu pažnju posvećujemo dodavanju izraza sa više reči (polileksemskih jedinica) koji se mogu smatrati uvredljivim, jer su takvi leksički zapisi veoma važni za postizanje dobrih rezultata u mnoštvu zadataka otkrivanja uvredljivog jezika. Srpski morfološki rečnici se koriste kao osnova za čišćenje podataka i stvaranje rečnika. Istaknuta je veza sa drugim leksičkim i semantičkim resursima na srpskom jeziku i predviđena je izgradnja sistema za ...... racial, national, and religious hate speech detection adopted by Gitari et al. (2015) was based solely on the usage of lexicon and rules. They used semantics and subjectivity features – polarity, intensity, and subjectivity level of words, using the domain corpus of hateful content and Subjectivity lexicon ...
... sentimental words and expressions, and SentiWordNet (Gitari et al., 2015), where it is assumed that abusive language consists of words indicating negative polarity of feelings, (3) list of offensive words and expressions (Bassignana et al., 2018) and (Hatebase.org), whether made by experts and/or obtained ...
... extensive use of online media and the Internet in gen- eral. The concept of abusive speech, as an umbrella term for phenomena such as offensive and hate speech, its content and forms of expression are analysed, trying to define its vocabulary, collocations, colloquial expressions, and context. Starting from ...Ranka Stanković, Jelena Mitrović, Danka Jokić, Cvetana Krstev. "Multi-word Expressions for Abusive Speech Detection in Serbian" in Proceedings of the Joint Workshop on Multiword Expressions and Electronic Lexicons, Association for Computational Linguistics (2020)
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Overwiew of In-Pit Crushing & Conveying Technology in Open Pit Mines
The conditions under which contemporary surface mining operations is carried out obviously becoming increasingly complex. In such complex conditions, the optimization of haulage systems as the technological phase with the largest share in the total operating costs, is very important from the aspect of achieving profitability of the mining project. In a large number of cases, the application of traditional haulage systems with trucks (as the most dominant type of haulage in open pit mines) does not lead to ...Ali Nasirinezhad, Dejan Stevanović, Dragan Ignjatović, Petar Marković. "Overwiew of In-Pit Crushing & Conveying Technology in Open Pit Mines" in 8th International Conference MIining And Environmental Protection, Sokobanja, 22-25 September 2021, University of Belgrade, Faculty of Mining and Geology, Belgrade, Serbia (2021)
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Understanding partitioning of deformation in highly arcuate orogenic systems: Inferences from the evolution of the Serbian Carpathians
Nemanja Krstekanić, Liviu Matenco, Marinko Toljić, Oleg Mandić, Uroš Stojadinović, Ernst Willingshofer (2020)... calculate and optimise reduced paleostress tensors (Figs. A.1, A.2 and Table A.1 of the Supplementary Appendix) by following a standard inversion approach with confidence criterion (e.g., Angelier, 1994; Angelier and Goguel, 1979; Angelier and Mechler, 1977; Delvaux and Sperner, 2003 and references ...
... (Lesić et al. (2019). These rotations and translations were associated with Eocene–early Miocene orogen-parallel extension and ~ 100 km of dextral strike-slip offset along the curved Cerna–Jiu and Timok faults system in the South and Serbian Carpathians, and a gradual transtensive opening of basins ...
... Global and Planetary Change 195 (2020) 103361 4 Fig. 2. Tectonic map of the Serbian Carpathians and adjacent areas of the South Carpathians and Balkanides showing the regional fault kinematics (compiled and modified after Basic geological map of former Yugoslavia, scale 1:100.000 and Maţenco, ...Nemanja Krstekanić, Liviu Matenco, Marinko Toljić, Oleg Mandić, Uroš Stojadinović, Ernst Willingshofer. "Understanding partitioning of deformation in highly arcuate orogenic systems: Inferences from the evolution of the Serbian Carpathians" in Global and Planetary Change, Elsevier BV (2020). https://doi.org/10.1016/j.gloplacha.2020.103361
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Concepts for Improving Machine Learning Based Landslide Assessment
Miloš Marjanović, Mileva Samardžić Petrović, Biljana Abolmasov, Uroš Đurić. "Concepts for Improving Machine Learning Based Landslide Assessment" in Natural Hazards GIS-based Spatial Modeling Using Data Mining Techniques, Advances in Natural and Technological Hazards Research, volume 48, Springer Nature Switzerland AG 2019 (2019). https://doi.org/10.1007/978-3-319-73383-8_2
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Heavy metals in lignite and soil of Kostolac-Kovin coal basin, eastern Serbia - comparative analysis with selected cities in Serbia, region, Europe and world
Bogoljub Vučković, Bojan Dimitrijević (2023)The Kostolac-Kovin coal basin with an area of 320 km2, with 5 separate layers of coal and with a total of about 5.7 Bt of geological resources and reserves represents an exceptional potential for coal production in Serbia. The coal resources listed in this way are not fully exploitable, but they represent potential for consideration. In this paper, we deal with the geochemical characteristics of coal seams and perform a comparative analysis of coal affectation on the environment. With ...... pits of Stari Kostolac and Ćirikovac, after that in the surface mines of Klenovnik and Cirikovac, picture 2) and are not being excavated now; 177 2. Now in the excavation phase are some parts of 1, II and III layers (I and II layers in Kovin by underwater exploitation; II and III layers in the Drmno ...
... seams and perform a comparative analysis of coal af}ectation on the environment. P/ith 155 analyzes of HM from coal, 45 from ash, 165 from gravel and 30 from soil, we perform analysis of horizontal and vertical distribution of HM and comparative analysis. B/hat interests us as authors and you as ...
... the Velika Morava and Mlava rivers, which flow into the Danube in that area (figure 1 and 2). Itis divided into two parts by the Danube - to the south is the Kostolac Basin, and to the north ofthe Danube is the Kovin Basin (Figure 2). Geological explorations began in 1941 and continues to this day ...Bogoljub Vučković, Bojan Dimitrijević. "Heavy metals in lignite and soil of Kostolac-Kovin coal basin, eastern Serbia - comparative analysis with selected cities in Serbia, region, Europe and world" in 9th International Conference Mining and Environmental Protection, 24–27. May 2023, Sokobanja, Beograd : Univerzitet u Beogradu, Rudarsko-geološki fakultet (2023)
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Application of the VIKOR Method for Selecting the Purpose of Recultivated Terrain after the End of Coal Mining
Radmila Gaćina, Sanja Bajić, Bojan Dimitrijević, Tomislav Šubaranović, Čedomir Beljić, Dragoljub Bajić (2024)Radmila Gaćina, Sanja Bajić, Bojan Dimitrijević, Tomislav Šubaranović, Čedomir Beljić, Dragoljub Bajić. "Application of the VIKOR Method for Selecting the Purpose of Recultivated Terrain after the End of Coal Mining" in Proceedings of the Bulgarian Academy of Sciences, Bulgaria, 28. maj 2024 , Prof. Marin Drinov Publishing House of BAS (Bulgarian Academy of Sciences) (2024). https://doi.org/10.7546/CRABS.2024.07.10
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Machine learning based landslide assessment of the Belgrade metropolitan area: Pixel resolution effects and a cross-scaling concept
Improvements of Machine Learning-based landslide prediction models can be made by optimizing scale, customizing training samples to provide sets with the best examples, feature selection, etc. Herein, a novel approach, named Cross-Scaling, is proposed that includes the mixing of training and testing set resolutions. Hypothetically, training on a coarser resolution dataset and testing the model on a finer resolution should help the algorithm to better generalize ambiguous examples of landslide classes and yield fewer over/underestimations in the model. This ...Uroš Đurić, Miloš Marjanović, Zoran Radić, Biljana Abolmasov. " Machine learning based landslide assessment of the Belgrade metropolitan area: Pixel resolution effects and a cross-scaling concept" in Engineering Geology , Elsevier (2019). https://doi.org/10.1016/j.enggeo.2019.05.007
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Two approaches to compilation of bilingual multi-word terminology lists from lexical resources
In this paper, we present two approaches and the implemented system for bilingual terminology extraction that rely on an aligned bilingual domain corpus, a terminology extractor for a target language, and a tool for chunk alignment. The two approaches differ in the way terminology for the source language is obtained: the first relies on an existing domain terminology lexicon, while the second one uses a term extraction tool. For both approaches, four experiments were performed with two parameters being ...Branislava Šandrih, Cvetana Krstev, Ranka Stanković. "Two approaches to compilation of bilingual multi-word terminology lists from lexical resources" in Natural Language Engineering, Cambridge University Press (CUP) (2020). https://doi.org/10.1017/S1351324919000615
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Antioxidant and antimicrobial activity of some tetradentate Schiff bases and their Cu (II) complexes
Aleksandar Mijatović, Milan Nikolić, Snežana Spasić, Aleksandra N. Žerađanin, Kristina Joksimović, Aleksandar Lolić, Rada Baošić (2020)Šifove baze i njihovi Cu(II) kompleksi su poznati po svojoj biološkoj aktivnosti. U ovom radu proučavana je antibakterijska aktivnost protiv gram-negativnih sojeva Escherichia coli, Pseudomonas aeruginosa i Staphilococcus piogenes, kao i Gram-pozitivnih Staphilococcus piogenes i Pseudomonas aeruginosa, zajedno sa antifungalnim dejstvom protiv Musperg strainilusa, A. Takođe, tehnički jednostavni i brzi testovi kao što su ABTS, HORAC i ORAC korišćeni su za ispitivanje antioksidativne aktivnosti kako bi se uporedili dobijeni rezultati sa različitim tipovima testova. Uprkos tome što je princip ...Aleksandar Mijatović, Milan Nikolić, Snežana Spasić, Aleksandra N. Žerađanin, Kristina Joksimović, Aleksandar Lolić, Rada Baošić. "Antioxidant and antimicrobial activity of some tetradentate Schiff bases and their Cu (II) complexes" in XIII Conference of Chemists, Technologists and Environmentalists of Republic of Srpska, University in Banjaluka, Faculty of Technology (2020)
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Linear-motor plunger pump increases lifting efficiency
Bojan Martinović, Dušan Đekić, Dušan Danilović, Pavel Isaev. "Linear-motor plunger pump increases lifting efficiency" in Oil & Gas Journal (2022)
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Long-term planning methodology for improving wood biomass utilization
The insufficiently developed forest management system is often followed by undeveloped forest resources supply chain and insufficient institutional support. These cause inefficient usage of fuel-wood as well as huge amounts of unused forest residues. In order to achieve optimal and long-term sustainable utilisation of biomass, an original methodology based on the interaction of mathematical optimization and backcasting approach has been developed. Mathematical optimization is used for both generation and consideration of techno-economic parameters of the forest biomass supply chain. ...Vladimir Vukašinović, Dušan Gordić, Marija Živković, Davor Koncalović, Dubravka Živković. "Long-term planning methodology for improving wood biomass utilization" in Energy, Elsevier BV (2019). https://doi.org/10.1016/j.energy.2019.03.105
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Effects of external noise on threshold-induced correlations in ferromagnetic systems
Dragutin Jovković, Sanja Janićević, Svetislav Mijatović, Lasse Laurson, Đorđe Spasojević. "Effects of external noise on threshold-induced correlations in ferromagnetic systems" in Physical Review E, American Physical Society (APS) (2021). https://doi.org/10.1103/PhysRevE.103.062114
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Bridging Computational Lexicography and Corpus Linguistics: A Query Extension for OntoLex-FrAC
OntoLex, dominantni standard zajednice za mašinski čitljive leksičke resurse u kontekstu RDF-a, Linked Data i tehnologija Semantičkog veba, trenutno se proširuje sa posebnim modulom za Frekvencije, Primere i Informacije zasnovane na Korpusu (OntoLex-FrAC). Predlažemo novi komponent za OntoLex-FrAC, koji se bavi inkorporacijom korpusnih upita za (a) povezivanje rečnika sa korpusnim mašinama, (b) omogućavanje RDF baziranih web servisa da dinamički razmenjuju korpusne upite i podatke odgovora, i (c) korišćenje konvencionalnih upitačkih jezika za formalizaciju unutrašnje strukture kolokacija, skica reči i ...standardizacija, digitalna leksikografija, OntoLex, upiti korpusa, povezani podaci, Lingvistički povezani otvoreni podaciChristian Chiarcos, Ranka Stanković, Maxim Ionov, Gilles Sérasset. "Bridging Computational Lexicography and Corpus Linguistics: A Query Extension for OntoLex-FrAC" in Proceedings of the 2024 Joint International Conference on Computational Linguistics, Language Resources and Evaluation (LREC-COLING 2024), Turin, 20-25 May 2024, LREC (2024)
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Regional Slope Stability Analysis in Landslide Hazard Assessment Context, North Macedonia Example
Miloš Marjanović, Biljana Abolmasov, Igor Peshevski, James Reeves, Irena Georgievska. "Regional Slope Stability Analysis in Landslide Hazard Assessment Context, North Macedonia Example" in Understanding and Reducing Landslide Disaster Risk, Springer International Publishing (2020). https://doi.org/10.1007/978-3-030-60227-7_29
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Curcumin nanonization using an alternative small-scale production unit: selection of proper stabilizer applying basic physicochemical consideration and biological activity assessment of nanocrystals
Ines Nikolić, Jelena Antić-Stanković, Dragana Božić, Danijela Ranđelović, Bojan Marković, Dominique Jasmin Lunter, Aleksandar Kremenović, Miroslav Savić, Snežana Savić (2020)As the number of poorly soluble drugs is increasing, nanocrystals have become very interesting due to wide range of application possibilities. Curcumin was used as a model active ingredient in this work. Even though it has many proven positive effects, due to its physicochemical issues, its possibilities have not been fully exploited. The goal of this work was to select optimal conditions for a top-down method for curcumin nanosuspension production, and to perform their comprehensive characterization applying complementary methodologies: ...Ines Nikolić, Jelena Antić-Stanković, Dragana Božić, Danijela Ranđelović, Bojan Marković, Dominique Jasmin Lunter, Aleksandar Kremenović, Miroslav Savić, Snežana Savić. "Curcumin nanonization using an alternative small-scale production unit: selection of proper stabilizer applying basic physicochemical consideration and biological activity assessment of nanocrystals" in Review on advanced materials science, Walter de Gruyter GmbH (2020). https://doi.org/10.1515/rams-2020-0043
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A Lexical Approach to Acronyms and their Definitions
In this paper we present a comprehensive approach to acronyms for Natural-Language Processing (NLP) of Serbian texts. The proposed procedure includes extraction of acronyms and their definitions that are usual Multi-Word Units (MWUs), shallow parsing of MWUs that enables MWU lemmatization and production of entries in morphological electronic dictionaries, both for MWU and acronyms, that are provided with grammatical, syntactic, semantic and domain information. This approach enables representation that reflects complex relations between acronyms and their definitions.... texts (57% daily, 8% weekly and 5% monthly newspapers) and 6% of monographs and textbooks (Krstev and Vitas, 2005), which are types of texts that tend to use acronyms and pro- vide definitions. Besides that we used two more samples of newspaper texts (having 600 thousand and 1.200 thousand simple word ...
... Electronic Communication and Postal Services’. Moreover, in many cases a relation between an entity and its name and acronym is not one-to-one. The name can change in time and some shortened variants can be in use, translated names can exhibit serious variations in used lexica and syntactic forms, original ...
... of Education and Science under grants 47003 and 178003. 6. References Jacobs, K., A. Itai, and S. Wintner, 2014. Acronym Dic- tionary Construction and Disambiguation (abstract). 3rd Parseme General Meeting – Poster Session. Krstev, C., R. Stanković, I. Obradović, D. Vitas, and M. Utvić, 2010 ...Cvetana Krstev, Duško Vitas, Ranka Stanković. "A Lexical Approach to Acronyms and their Definitions" in Proceedings of the 7th Language & Technology Conference, November 27-29, 2015, Poznań, Poland, Springer (2015)