... the antiapoptotic Bcl-2 protein was associ-
ated with sensitization of cancer cells to apoptosis [48]. The mechanism of action of
these inhibitors was dependent on their binding to the binding groove in Bcl-2, which
resulted in inhibition of the antiapoptotic effect of Bcl-2. To investigate the ...
... by a hydrogen bond.
Figure 9. Best pose docked into protein Bcl-2 for 3 according to the Hbond values: (A) molecular
docking results illustrated regarding the Bcl-2 protein's backbone; (B) binding site of investigated
complex on Bcl-2 protein and selected amino acid residues (selected by applying ...
... ON CHEMISTRY @ 17
Figure 10. Best pose docked into protein Bcl-2 for 6 according to the Hbond values: (A) molecular
docking results illustrated regarding the Bcl-2 protein's backbone; (B) binding site of investigated
complex on Bcl-2 protein and selected amino acid residues (selected by applying ...
Milica Međedović, Dušan Ćoćić, Aleksandar Mijatović, Vladimir Simić, Žiko Milanović, Marijana Kosanić, Nevena Petrović, Snežana Sretenović, Ana Rilak Simović. "In silico and in vitro biological evaluation: distribution of Ru(III) Schiff base complexes through the pancreatic 3D model and immersed blood vessel network" in Journal of Coordination Chemistry, Informa UK Limited (2024). https://doi.org/10.1080/00958972.2024.2303736
