Претрага
240 items
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Human Hemoglobin and Antipsychotics Clozapine, Ziprasidone and Sertindole: Friends or Foes?
Lena Platanić Arizanović, Nikola Gligorijević, Ilija Cvijetić, Aleksandar Mijatović, Maja Krstić Ristivojević, Simeon Minić, Aleksandra Nikolić Kokić, Čedo Miljević, Milan Nikolić (2023)Packed with hemoglobin, an essential protein for oxygen transport, human erythrocytes are a suitable model system for testing the pleiotropic effects of lipophilic drugs. Our study investi gated the interaction between antipsychotic drugs clozapine, ziprasidone, sertindole, and human hemoglobin under simulated physiological conditions. Analysis of protein fluorescence quenching at different temperatures and data obtained from the van’t Hoff diagram and molecular docking indicate that the interactions are static and that the tetrameric human hemoglobin has one binding site for ...Inorganic Chemistry, Organic Chemistry, Physical and Theoretical Chemistry, Computer Science Applications, Spectroscopy, Molecular Biology, General Medicine, CatalysisLena Platanić Arizanović, Nikola Gligorijević, Ilija Cvijetić, Aleksandar Mijatović, Maja Krstić Ristivojević, Simeon Minić, Aleksandra Nikolić Kokić, Čedo Miljević, Milan Nikolić. "Human Hemoglobin and Antipsychotics Clozapine, Ziprasidone and Sertindole: Friends or Foes?" in International Journal of Molecular Sciences, MDPI AG (2023). https://doi.org/10.3390/ijms24108921
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Fluid inclusion study in quartz of the Rudnik Pb-Zn-Cu-Ag skarn deposit, Serbia
Six types of fluid inclusions were identified in three growth zones of hydrothermal quartz from the Rudnik skarn deposit. In the core zone, primary two-phase fluid inclusions of high (type 1) and moderate salinity (type 2) homogenized to liquid between 350-430 °C and 340-420 °C, respectively. Raman analysis revealed that the vapour phases are a CO2-CH4 gas mixture, with a predominance of CO2. The core contains and dispersed vapour-rich fluid inclusions of low salinity (type 3) composed of CO2-CH4-H2S ...Stefan Petrović, Ronald J. Bakker, Vladica Cvetković, Rade Jelenković. "Fluid inclusion study in quartz of the Rudnik Pb-Zn-Cu-Ag skarn deposit, Serbia" in Mineral Resources in a Changing World-17th SGA Biennial Meeting, Zurich, between 28th August and 1st September 2023, Genéve : Society for Geology Applied to Mineral Deposits (2023)
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The first record of nautiloids (Cenoceras intermedius) from the early Pliensbachian of Rgotina, (Getic nappe, eastern Serbia)
Cenoceras intermedius (J. Sowerby) is one of the most widespread species among the Early Jurassic nautiloid fauna and its geological range still controversial up to the present day. The specimen of Cenoceras intermedius from the sandy bioclastic limestones of Rgotina (Getic nappe of eastern Serbia), is a large half conch representing the phragmocone. Viewing our findings in light of previous results suggests the main morphological changes occurred during the ontogenetic evolution. The coiling starts with a round-square whorl section, ...Cephalopoda, Cenoceras intermedius, ontogenetic changes, geological range, northwestern Neo-Tethys, PliensbachianPaul Țibuleac, Barbara V. Radulović, Marinko Toljić. "The first record of nautiloids (Cenoceras intermedius) from the early Pliensbachian of Rgotina, (Getic nappe, eastern Serbia)" in Historical Biology, Informa UK Limited (2020). https://doi.org/10.1080/08912963.2020.1821003
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Hybrid Model for Optimisation of Waste Dump Design and Site Selection in Open Pit Mining
Aleksandar Doderovic, Svetozar-Milan Doderovic, Sasa Stepanovic, Mirjana Bankovic, Dejan Stevanovic (2023)Waste management is an unavoidable technological operation in the process of raw material extraction. The main characteristic of this technological operation is the handling of large quantities of waste material, which can amount to several hundred million cubic metres. At the same time, this operation must comply with all administrative and environmental standards. Therefore, optimising waste rock management (particularly haulage and dumping) has the potential to significantly improve the overall value of the project. This paper presents a hybrid ...Aleksandar Doderovic, Svetozar-Milan Doderovic, Sasa Stepanovic, Mirjana Bankovic, Dejan Stevanovic. "Hybrid Model for Optimisation of Waste Dump Design and Site Selection in Open Pit Mining" in Minerals, MDPI AG (2023). https://doi.org/10.3390/min13111401
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Organoselenium functionalized oxacycles as ligands in some trans-palladium(II) complexes: biological evaluation and interaction with small biomolecules
I. Raković, D. Ćoćić, O. Milošević-Djordjević, I. Radojević, M. N. Živanović, K. Virijević, J. Pavić, J. Tubić Vukajlović, A. Marković, J. S. Marjanović, M. D. Kostić, P. Čanović, A. Mijatović, V. M. Divac (2023)In this article, the biological evaluation and interaction of three selenium-based trans-palladium complexes (Pd–Se1, Pd–Se2, and Pd–Se3) with small biomolecules were performed. The UV–Vis kinetic studies on substitution reaction of synthesized complexes with selected biologically important N- and S-bonding ligands (LCys, GSH, L-Met, 50-GMP, L-His) has emphasized greater affinity of sulphur-based ligands for complex-binding, while the general order of the reactivity was L-Cys > GSH > L-Met > 50-GMP > L-His. The complex reactivity toward small biomolecules is influenced ...I. Raković, D. Ćoćić, O. Milošević-Djordjević, I. Radojević, M. N. Živanović, K. Virijević, J. Pavić, J. Tubić Vukajlović, A. Marković, J. S. Marjanović, M. D. Kostić, P. Čanović, A. Mijatović, V. M. Divac. "Organoselenium functionalized oxacycles as ligands in some trans-palladium(II) complexes: biological evaluation and interaction with small biomolecules" in Journal of Coordination Chemistry, Informa UK Limited (2023). https://doi.org/10.1080/00958972.2023.2256934
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Оцјена водопропусности понорске зоне Шуковићу (Цернићко поље) помоћу Лижоновог теста
One of the specificities of reservoirs forming in highly karstified terrains is reflected in the wide range of unknowns, specifically during reservoir formation, filling and operation. Unfortunately, despite complex research, many reservoirs constructed in karst terrains have problems with water losses from the reservoir to other aquifers due to ponor and ponor zones which are a common in the karst of Eastern Herzegovina. One of such zones is Šuković ponor located in the southern part of the Cerničko polje ...Петар Војновић, Саша Милановић, Љиљана Васић. "Оцјена водопропусности понорске зоне Шуковићу (Цернићко поље) помоћу Лижоновог теста " in Мултидисциплинарна конференција “Kарст 2022 - Значај, стање и перспективе коришћења и заштите ресурса у карсту", Српска академија наука и уметности (2022)
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In vitro and in silico study of the biological activity of tetradentate Schiff base copper(II) complexes with ethylenediamine-bridge
Aleksandar Mijatović, Nevenka Gligorijević, Dušan Ćoćić, Snežana Spasić, Aleksandar Lolić, Sandra Aranđelović, Milan Nikolić, Rada Baošić (2023)The biological activity of six structurally similar tetradentate Schiff base copper(II) complexes, namely [Cu(ethylenediamine-bis-acetylacetonate)] (CuAA) and five derivatives where two methyl groups are replaced by phenyl, (CuPP), CF3 (CuTT) or by mixed groups CH3/CF3 (CuAT), Ph/CF3 (CuPT), and Ph/CH3 (CuAP) has been investigated. The set of antioxidant assays was performed, and the results were expressed as IC50 and EC50 values. The series of complexes showed interesting bioactivity and were investigated for the determination of antioxidant, antifungal, antimicrobial, and cytotoxic ...Aleksandar Mijatović, Nevenka Gligorijević, Dušan Ćoćić, Snežana Spasić, Aleksandar Lolić, Sandra Aranđelović, Milan Nikolić, Rada Baošić. "In vitro and in silico study of the biological activity of tetradentate Schiff base copper(II) complexes with ethylenediamine-bridge" in Journal of Inorganic Biochemistry, Elsevier BV (2023). https://doi.org/10.1016/j.jinorgbio.2023.112224
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Micro- to nanoscale textures of gold in arsenopyrite and scorodite from the As-Au-Bi assemblage of Drenjak locality (Serbia)
Ivana Jelić, Janez Zavašnik, Marina Lazarov, Alena Zdravković, Sabina Kovač, Jovica Stojanović, Aleksandar Pačevski (2023)Arsenopyrite and pyrite are important carriers of Au that is present in the form of microscopic and “invisible” gold. Such gold can be expected to be released upon the process of oxidation of these sulfides. In studied gold mineralization at Drenjak, related to the granitoids of the Oligocene-Miocene Kopaonik Ore District, the main arsenopyrite-pyrite-(bismuthinite) sulfide assemblage was formed in the quartz bodies and partly replaced by scorodite (FeAsO4·2H2O) and Bi-arsenate. With only up to 5 ppm of gold recorded ...Ivana Jelić, Janez Zavašnik, Marina Lazarov, Alena Zdravković, Sabina Kovač, Jovica Stojanović, Aleksandar Pačevski. "Micro- to nanoscale textures of gold in arsenopyrite and scorodite from the As-Au-Bi assemblage of Drenjak locality (Serbia)" in Ore Geology Reviews, Elsevier BV (2023). https://doi.org/10.1016/j.oregeorev.2023.105711
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Mio-Pliocene Geodynamics and its Stratigraphic Consequences in the Area of Avala Mt. (Belgrade, Serbia)
... geology, Kamenička 6, 11000 Belgrade, Serbia *corresponding author: ljupko.rundic@rgf.bg.ac.rs In recent years, thanks to numerous infrastructural works and construction of the local roads, new outcrops and sections near Avala Mt. have been discovered. Especially, on the left bank of the Rakovica stream ...
... geology, Kamenicka 6, 11000 Belgrade, Serbia *corresponding author: ljupko.rundic@raf.bg.ac.rs In recent years, thanks to numerous infrastructural works and construction of the local roads, new outcrops and sections near Avala Mt. have been discovered. Especially, on the left bank of the Rakovica stream ...Ljupko Rundić, Meri Ganić, Slobodan Knežević, Dejan Radivojević. "Mio-Pliocene Geodynamics and its Stratigraphic Consequences in the Area of Avala Mt. (Belgrade, Serbia)" in 7th International Workshop: Neogene of Central and South-Eastern Europe, Velika, Croatia, maj 2017, Croatian Geological Society (2017)
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Structure, interaction with biomolecules, and cytotoxicity of copper (II) complexes chelating some Schiff base ligands
Aleksandar Mijatović, Angelina Z. Caković, Aleksandar Lolić, Olivera Klisurić, Marko N. Živanović, Dragana S. Šeklić, Snežana Sretenović, Marija Ilić, Jovana Bogojeski (2023)Cancer remains one of the world's deadliest diseases, claiming many lives each day. Transition metal complexes are leading candidates in developing anticancer agens with cisplatin used in chemotherapy worldwide. Copper, an endogenous metal in the human body, is especially attractive because of its typical redox biological activities and a relatively strong affinity to nucleobases. A series of Cu(II) complexes with ethane-1,2-diamine as the amine part and pentane-2,4-dione and/or 1-phenylbutane-1,3-dione, pentane-2,4-dione and/or 1,1,1- trifluoropentane-2,4-dione, or 1,1,1-trifluoropentane-2,4-dione and/or 1-phenylbutane-1,3-dione as the ...Aleksandar Mijatović, Angelina Z. Caković, Aleksandar Lolić, Olivera Klisurić, Marko N. Živanović, Dragana S. Šeklić, Snežana Sretenović, Marija Ilić, Jovana Bogojeski. "Structure, interaction with biomolecules, and cytotoxicity of copper (II) complexes chelating some Schiff base ligands" in Applied Organometallic Chemistry, Wiley (2023). https://doi.org/10.1002/aoc.7253
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Uporedni prikaz proizvodnje električne energije iz uglja zemalja Evrope sa najvećim udelom: politika i projekcija proizvodnje
Energetski razvoj zemalja Evrope decenijama je bio baziran na uglju. Instalisana snaga svih energetskih kapaciteta koji su zasnovani na uglju je preko 2000 GW. Ugalj je i dalje od bitnog značaja za dobijanje električne energije u Evropi. I pored toga što postoji veliki potencijal uglja, trend je smanjenja proizvodnje električne energije iz uglja do 2050. godine. Imajući u vidu Zelenu agendu i politiku EU, zemlje Evrope se okreću obnovljivim izvorima energije. Srbija u okviru obnovljvih izvora ima potencijala prevashodno ...Predrag Jovančić, Dragan Ignjatović, Stevan Đenadić. "Uporedni prikaz proizvodnje električne energije iz uglja zemalja Evrope sa najvećim udelom: politika i projekcija proizvodnje" in Energija, ekonomija, ekologija, Savez energetičara (2022). https://doi.org/10.46793/EEE22-3.63J
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Koncept prediktivnog održavanja 4.0 (PdM) u energetici – konekcija sa budućom primenom Industrije 5.0
Četvrtu industrijsku revoluciju - Industrija 4.0 karakteriše upotreba cyber-fizičkih sistema. Da bi se postigla optimalna strategija održavanja (ali i proizvodnje), neophodno je razviti sisteme koji podržavaju napredne inteligentne sisteme održavanja ili tehnologije pametnog održavanja. Iz toga su proizašli postulati Prediktivnog održavanja 4.0 koji definišu veoma blisku budućnost u oblasti održavanja tehničkih sistema. Prediktivno održavanje 4.0 uključuje iskorišćenje snage veštačke inteligencije za stvaranje stalnog uvida u otkrivanje uzroka i anomalija u radu opreme, koje se ne otkrivaju kognitivnim moćima. Drugim ...Predrag Jovančić, Dragan Ignjatović, Stevan Đenadić, Miloš Tanasijević, Filip Miletić. "Koncept prediktivnog održavanja 4.0 (PdM) u energetici – konekcija sa budućom primenom Industrije 5.0" in Energija, ekonomija, ekologija, Savez energetičara (2022). https://doi.org/ 10.46793/EEE22-2.54J
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Synthesis, characterization, biomolecular interactions, molecular docking, and in vitro and in vivo anticancer activities of novel ruthenium(III) Schiff base complexes
Milica Međedović, Aleksandar Mijatović, Rada Baošić, Dejan Lazić, Žiko Milanović, Zoran Marković, Jelena Milovanović, Dragana Arsenijević, Bojana Stojanović, Miloš Arsenijević, Marija Milovanović, Biljana Petrović, Ana Rilak Simović (2023)In order to discover new anticancer drugs, novel ruthenium(III) complexes [Ru(L)Cl(H2O)], where L is tetradentate Schiff base bis(acetylacetone)ethylendiimine (acacen, 1), bis(benzoylacetone)ethylendiimine (bzacen, 2), (acetylacetone)(benzoylaceton)ethylendiimine (acacbzacen, 3), bis(acetylacetone)propylendiimine (acacpn, 4), bis(benzoylacetone)propylendiimine (bzacpn, 5) or (acetylacetone)(benzoylaceton)propylendiimine (acacbzacpn, 6), were synthesized. The complexes 1 – 6 were characterized by elemental analysis, molar conductometry, and by various spectroscopic techniques, such as UV–Vis, IR, EPR, and ESI-MS. Based on in vitro DNA/BSA experiments, complexes 2 (bzacen) and 5 (bzacpn) with two aromatic rings showed ...Milica Međedović, Aleksandar Mijatović, Rada Baošić, Dejan Lazić, Žiko Milanović, Zoran Marković, Jelena Milovanović, Dragana Arsenijević, Bojana Stojanović, Miloš Arsenijević, Marija Milovanović, Biljana Petrović, Ana Rilak Simović. "Synthesis, characterization, biomolecular interactions, molecular docking, and in vitro and in vivo anticancer activities of novel ruthenium(III) Schiff base complexes" in Journal of Inorganic Biochemistry, Elsevier BV (2023). https://doi.org/10.1016/j.jinorgbio.2023.112363
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Depth geological relations of the wider area of Belgrade - based on the wells and geophysical data
Đorđe Marinović, Ljupko Rundić (2020)Предметна референца обухвата простор шире околине Београда укупне површине око 2.000 km2. Аутори су објединили капиталне геолошке и геофизичке податке обезбеђене површинским истраживањима и мултидисциплинарним елементима из 52 бушотинe са дубинама између 33 и 2.733 m. Конкретни палеонтолошки налази специјализованих аналитичара са детерминацијом макро и микрофауне и флоре, презентовани су како из неогених формација тако и из басенске подине. Осим конвенционалних петролошких описа стена цитиране су и микроскопске детерминације интрузивних и екструзивних магматита. Из затвореног басенског простора корелативно су ...Đorđe Marinović, Ljupko Rundić. "Depth geological relations of the wider area of Belgrade - based on the wells and geophysical data" in Annales geologiques de la Peninsule balkanique, National Library of Serbia (2020). https://doi.org/10.2298/GABP201030009M
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Cretaceous ultrapotassic magmatism from the Sava-Vardar Zone of the Balkans
Kristijan Sokol, Dejan Prelević, Rolf Romer, Milica Božović, Paul van den Bogaard, Elitsa Stefanova, Bojan Kostić, Nenad Čokulov (2020)Late Cretaceous global plate reorganization associated with the inception of counterclockwise rotation of Africa relative to Europe initiated in the Balkan region small-volume magmatism of diverse geochemical signature along the enigmatic Sava-Vardar Zone. We study a Late Cretaceous lamprophyric sill in Ripanj village near Belgrade to constrain this magmatic episode. The lamprophyre is characterized by high contents of Na, P, Fe and Al, and low contents of K, Ca and Mg. Its original nature (Na, K, Ca and Mg) is ...Kristijan Sokol, Dejan Prelević, Rolf Romer, Milica Božović, Paul van den Bogaard, Elitsa Stefanova, Bojan Kostić, Nenad Čokulov. "Cretaceous ultrapotassic magmatism from the Sava-Vardar Zone of the Balkans" in Lithos (2020)
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Complex geophysical survey on solving the problem of water loss in the karst terrain reservoir
Branislav Sretković, Dejan Vučković (2023)Geophysical surveys in karst terrain are always a specific challenge. Each of them requires a careful consideration of the problem, specific conditions on the ground, the selection of adequate methods applicable in that specific and unique karst area. But they should have one thing in common: a complex approach and looking at the problem from wider to narrower, with a gradual narrowing of the investigation area, increasing the spatial precision and resolution of the obtained data. On the example of ...Branislav Sretković, Dejan Vučković. "Complex geophysical survey on solving the problem of water loss in the karst terrain reservoir" in 8th Symposium Geoscience 2023, Bucharest, 9-11. November 2023, Bucharest : Editura Cetatea de Scaun (2023)
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Analiza primene višekriterijumskih metoda u optimizaciji izbora hidruličnih bagera na površinskim kopovima uglja
Hidraulični bageri primenjuju se u različitim oblastima privrede a najzastupljeniji su u građevinarstvu i rudarstvu. Na površinskim kopovima sa kontinualnim sistemima, klasifikuju kao pomoćna mehanizacija a na površinskim kopovima sa diskontinualnim sistemima, kao osnovna mehanizacija. Kako je u oba slučaja njihova primena neizostavna, važno je izvršiti adekvatnu analizu postojećih podataka, u cilju optimizacije izbora tipa hidrauličnog bagera u odnosu na uslove rada datog površinskog kopa. U radu su opisane različite višekriterijumske metode koje su korišćene za analizu hidrauličnih bagera. ...... in different areas of industry, most often in construction and mining. On open-cast coal mines with continuous systems, they are classified as auxiliary machinery, while on open- cast coal mines with discontinuous systems they are basic machinery. As their application is necessary in both cases ...
... output information which can affect the future purchasing decisions of this machinery. Key words: multi-criteria methods, open-cast coal mine, auxiliary machines, hydraulic excavators. https://doi.org/10.1016/j.procs.2015.07.081 https://doi.org/10.1016/j.procs.2015.07.081 ...Stevan Đenadić, Predrag Jovančić, Dragan Ignjatović, Filip Miletić, Ivan Janković. "Analiza primene višekriterijumskih metoda u optimizaciji izbora hidruličnih bagera na površinskim kopovima uglja" in Tehnika, Centre for Evaluation in Education and Science (CEON/CEES) (2019). https://doi.org/10.5937/tehnika1903369D
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Флотабилност халкопирита из полиметаличне руде рудника „Рудник”
Ђурица Н. Никшић (2022)The doctoral dissertation Chalcopyrite flotability from polymetallic "Rudnik" mine ore consists of two parts. The first part is a general part in which the theoretical foundations of the flotation concentration process, the flotation properties of chalcopyrite, the influence of certain flotation reagents and the mechanism of action on the flotation properties of chalcopyrite are presented. This part also describes the process of flotation concentration of polymetallic ore from the "Rudnik" mine. The second part is ...Ђурица Н. Никшић. Флотабилност халкопирита из полиметаличне руде рудника „Рудник”, Београд : [Ђ. Никшић], 2022
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Razvoj modela upravljanja cirkulacijom u postupku bušenja korišćenjem neuro fazi sistema zaključivanja
Seyed Ali S. Razeghi (2022)Gubitak isplake predstavlja nekontrolisano isticanje bušaćeg fluida kroz formacije kao što su kaverne, pukotine, ili drugi slojevi. Tradicionalne metode procene gubitka isplake se zasnivaju na primeni seizmičkih podataka ili pronalasku „mesta“ gubitka isplake na osnovu raspoloživih podataka iz susednih bušotina. Međutim, ove metode procene nisu pouzdane.‘ U disertaciji je izvršena analiza i procena uticaja parametara bušenja, geoloških faktora, karakteristika formacije i fluida na gubitak isplake kao i na formiranje fraktura u formacijama. Uspostavljeni su modeli koji podrazumevaju proces obrade ...Seyed Ali S. Razeghi. Razvoj modela upravljanja cirkulacijom u postupku bušenja korišćenjem neuro fazi sistema zaključivanja, Beograd : [S. Razeghi], 2022
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Стратешко планирање функционалности подземних просторија моделом прогнозе деформација
Лука Црногорац (2023)Релативно велике деформације подградне конструкције у подземним рудницима угља у Републици Србији представљају један од главних проблема за постизање планиране производње угља. Деформације подграде су директна последица статичких и динамичких оптерећења стенске масе и у многоме зависе и од времена трајања изложености подграде утицају подземног притиска. Код ниско механизованог радног процеса долази до повећаног излагања подземних просторија утицају подземног притиска услед дугог производног циклуса који је често пропраћен застојима у раду. Веома често подземне просторије се санирају и по ...Лука Црногорац. Стратешко планирање функционалности подземних просторија моделом прогнозе деформација, Београд : [Л. Црногорац], 2023